Research Paper Volume 12, Issue 24 pp 24957—24966

LINC01410 accelerated the invasion and proliferation of osteosarcoma by sponging miR-3128

Figure 6. LINC01410 overexpression increased osteosarcoma cell invasion and growth by modulating miR-3128. (A) Ectopic expression of miR-3128 inhibited the cell cycle in LINC01410-overexpressing MG-63 cells. (B) The expression of ki-67 was analyzed by qRT-PCR assay. (C) The expression of cyclin D1 was analyzed by qRT-PCR assay. (D) Overexpression of miR-3128 decreased the proliferation of LINC01410-overexpressing MG-63 cells. (E) The expression of N-cadherin was analyzed by qRT-PCR assay. (F) The expression of E-cadherin was analyzed by qRT-PCR assay. (G) The expression of Vimentin was analyzed by qRT-PCR assay. (H) The relative number of invasive cells is shown. *p<0.05, **p<0.01 and ***p<0.001.