Research Paper Volume 12, Issue 14 pp 14329—14340

Downregulation of hsa_circ_0007580 inhibits non-small cell lung cancer tumorigenesis by reducing miR-545-3p sponging

Figure 7. Hsa_circ_0007580 silencing inhibited the progression of NSCLC by inactivating MAPK signaling. (A) The protein levels of PRKCA, p38 and p-p38 in A549 cells were investigated through Western blotting. (B) The relative expression of PRKCA was quantified and normalized to that of β-actin. (C) The relative expression of p-p38 in A549 cells was quantified and normalized to that of β-actin. **P<0.01 vs. control.