Research Paper Volume 12, Issue 17 pp 16837—16851
Sulforaphane-cysteine downregulates CDK4 /CDK6 and inhibits tubulin polymerization contributing to cell cycle arrest and apoptosis in human glioblastoma cells
Figure 2. CDK4/CDK6 mRNA expression showed positive correlation to pathological grades and negative correlation to clinical prognosis. (A, E) The expression and survival analysis of mRNA CDK4/CDK6 in glioma patients were done via GEPIA Database, which matched TCGA normal and GTEx data. (B–D, F–H). The expression and survival analysis of mRNA CDK4/CDK6 in glioma patients with primary and recurrent were done via CGGA database. Data were shown as *P < 0.05; **P < 0.01; ***P < 0.001, NS no significance vs. control group, n ≥ 3.