Research Paper Volume 12, Issue 14 pp 14918—14932

RP11-295G20.2 facilitates hepatocellular carcinoma progression via the miR-6884-3p/CCNB1 pathway

Figure 8. Knockdown of RP11-295G20.2 suppresses tumor growth in vivo. (A) Quantitative analysis of the average tumour volume derived from si-RP11-295G20.2–transfected or si-NC–transfected HCC cells,*P < 0.05. (B) Representative images of tumours derived from the nude mice injected with si-RP11-295G20.2–transfected or si-NC–transfected HCC cells,*P < 0.05. (C) Quantitative analysis of the average tumour weights derived from si-RP11-295G20.2–transfected or si-NC–transfected HCC cells,*P < 0.05. (D, E) The relative expression of RP11-295G20.2, miR-6884-3p, and CCNB1 were detected using RT-qPCR (D, E) and western blot (F), *P < 0.05. (G) The mechanism hypothesis of RP11-295G20.2/miR-6884-3p/CCNB1 pathway in HCC.