Research Paper Volume 12, Issue 16 pp 16099—16110

IL-21 mediates microRNA-423-5p /claudin-5 signal pathway and intestinal barrier function in inflammatory bowel disease

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Figure 6. IL-21 regulates miR-423-5p in UC. (A) The expression of miR-423-5p in colorectal epithelial cell lines. n=8. (B) TEER was determined in Caco-2 cells. n=4. (C) The FD4 level was detected after si-miR-423-5p/si-NC transfection in IL-21 treated cells. n=5. (D) The expression of miR-423-5p in different groups. n=7. *P < 0.05, **P < 0.01.