Research Paper Volume 12, Issue 16 pp 16142—16154

LAIR-1 suppresses cell growth of ovarian cancer cell via the PI3K-AKT-mTOR pathway

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Figure 6. Identification and GO enrichment analysis of LAIR-1 binding proteins. The potential LAIR-1 binding protein was identified using Co-IP assay and mass spectrometry. (A) Coomassie brilliant blue staining of polyacrylamide gels loaded with the Co-IP samples. (B) Mass spectrum of one unique peptide THINIVVIGHVDSGK found in sp|Q05639|EF1A2_HUMAN, the most abundant LAIR-binding protein. (C, D) Top 10 significantly enriched GO terms in biological process and molecular function are displayed, respectively. Terms of same category are ordered by annotated level. Max Level: maximal annotated level of the corresponding term in the GO graph (tree). Information on percentage of proteins involved in the term is shown on the x-axis.