Research Paper Volume 12, Issue 17 pp 16899—16920
Umbilical cord mesenchymal stem cells protect thymus structure and function in aged C57 mice by downregulating aging-related genes and upregulating autophagy- and anti-oxidative stress-related genes
Figure 10. Changes in CK5 and CK8 expression in the thymus after treatment with mUCMSCs. Note: (A, B) are immunofluorescence staining images of thymus tissue in mice treated with mUCMSCs for 1 month; (C, D) are immunofluorescence staining images of mouse thymus tissue from the model control group; (E, F) show the thymus in the young control group. Immunofluorescence staining map. CK5 is red, and CK8 is green. Note: *** indicates p < 0.001; ** indicates p < 0.01; * indicates p < 0.05; NS is p > 0.05. Cytokeratin 8 (cK8) and cytokeratin 5 (cK5) are markers of the thymic cortex and medulla, respectively, as shown by the results of thymic staining with immunofluorescent antibodies.