Research Paper Volume 13, Issue 2 pp 1842—1858

Low DAPK1 expression correlates with poor prognosis and sunitinib resistance in clear cell renal cell carcinoma

ROC curve analysis shows diagnostic significance of DAPK1 expression in ccRCC patients. (A) ROC curve analysis shows that DAPK1 expression accurately distinguishes ccRCC tissues from the corresponding normal kidney tissues with an AUC value of 0.6602 (95% CI: 0.6056 to 0.7148; pB–E) ROC curve analysis shows that DAPK1 expression distinguishes advanced- and early-stage ccRCC patients based on (B) T stages (T1+T2 vs. T3+T4), (C) pathologic Stages (I+II vs. III+IV), (D) G stages (G1+G2 vs. G3+G4), and (E) M stages (M0 vs. M1).

Figure 3. ROC curve analysis shows diagnostic significance of DAPK1 expression in ccRCC patients. (A) ROC curve analysis shows that DAPK1 expression accurately distinguishes ccRCC tissues from the corresponding normal kidney tissues with an AUC value of 0.6602 (95% CI: 0.6056 to 0.7148; p<0.0001). (BE) ROC curve analysis shows that DAPK1 expression distinguishes advanced- and early-stage ccRCC patients based on (B) T stages (T1+T2 vs. T3+T4), (C) pathologic Stages (I+II vs. III+IV), (D) G stages (G1+G2 vs. G3+G4), and (E) M stages (M0 vs. M1).