Research Paper Volume 12, Issue 17 pp 17122—17136

Long non-coding RNA SNHG12 promotes immune escape of ovarian cancer cells through their crosstalk with M2 macrophages

class="figure-viewer-img"

Figure 6. SNHG12 depletion suppresses immune escape in vivo. (A) Weight of mice recorded every 3 d. (B) Growth curve of transplanted tumor recorded every 5 d. (C) image of transplanted tumors (Scale = 1 mm). (D) CD3+ cells in transplanted tumors determined by IHC. (E) the rate of IFN-γ positive cells in transplanted tumors determined by flow cytometry. * p < 0.05 vs. SKOV3 + T cells. Statistical comparisons were performed using unpaired t test when only two groups were compared or by Tukey’s test-corrected one-way ANOVA with when more than two groups were compared. Variables were analyzed at different time points using Bonferroni-corrected repeated measures ANOVA.