Research Paper Volume 12, Issue 17 pp 17150—17166

LNK deficiency decreases obesity-induced insulin resistance by regulating GLUT4 through the PI3K-Akt-AS160 pathway in adipose tissue

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Figure 3. LNK deficiency influences adipose metabolism and systemic inflammation. Fasting total cholesterol (A), triglyceride (B), HDL (C), LDL (D), apolipoprotein (E), free fatty acid (F), high-sensitivity c-reactive protein (G) levels in mice serum at week 16 on the HFD or NCD feeding. HFD: LNK-/- n=7, WT n=6; NCD: LNK-/- n=6, WT n=7. Bars indicate mean ± SD. Statistical analysis was performed by One-way analysis of variance (ANOVA). *p < 0.05, **p < 0.01, ***p < 0.001.