Research Paper Volume 12, Issue 17 pp 17288—17294

Male patients with TERT mutation may be more likely to benefit from immunotherapy, especially for melanoma

Figure 1. The differential mutant genes between female vs male group. (A) Scatter plots, the altered frequency of genetic mutations between female vs male group (%). The X axis represents altered frequency in female. The Y axis represents altered frequency in male. The blue dots indicate that the p and q values are statistically significant. (B) The top 10 genes with the greatest difference of mutations between female vs male group. The X axis represents genetic changes with the greatest difference. The Y axis represents differential mutant genes. The red histogram indicates female and the blue histogram indicates male. (C) The frequency of TERT mutations between female vs male group in different cancer types. X-axis represents common types of cancer. The Y axis represents percent of TERT mutation. The red histogram indicates female and the blue histogram indicates male.