Research Paper Volume 12, Issue 20 pp 20152—20162

Polymerase I and transcript release factor transgenic mice show impaired function of hematopoietic stem cells


PTRF altered the expression pattern of senescence-associated genes in LSKs. (AC) RT-PCR analysis of the indicated genes in sorted LSK cells from PTRF and WT mice. Data represent the mean ± SD of three independent experiments. *, P < 0.05; **, P < 0.01. Data were normalized against GAPDH expression.