Research Paper Volume 13, Issue 10 pp 14499—14521

Identification of a 15-pseudogene based prognostic signature for predicting survival and antitumor immune response in breast cancer

Pseudogene-miRNA-target gene regulatory networks. Nine pseudogenes together with binding miRNAs and target genes with |r| ≥ 0.3 and P A) and oncogene pseudogenes (B). Pink hexagons represented pseudogenes, which are located at the cores of the networks. Tomato ellipses and blue round rectangles stand for binding miRNAs and target genes, respectively.

Figure 6. Pseudogene-miRNA-target gene regulatory networks. Nine pseudogenes together with binding miRNAs and target genes with |r| ≥ 0.3 and P < 0.05 were used to construct the pseudogene-miRNA-target gene regulatory networks by subgroups of tumor-suppressor pseudogenes (A) and oncogene pseudogenes (B). Pink hexagons represented pseudogenes, which are located at the cores of the networks. Tomato ellipses and blue round rectangles stand for binding miRNAs and target genes, respectively.