Research Paper Advance Articles

Transcriptional regulation of miR-483-3p mediated by IL-6/STAT3 axis promoted epithelial-mesenchymal transition and tumor stemness in glioma

Figure 1. MiR-483-3p levels in different glioma cell lines and in glioma tissue of human and mice. (AC) qRT-PCR analysis showed upregulation of miR-483-3p in cancer tissues and different cancer cell lines. Data are mean ± SEM; Two-tailed t test was used for the statistical analysis. n= 50 glioma patients or 6 mice per group or 5 independent cell cultures. (D) The 5-year survival rate of high and low miR-483-3p level patients. Data are mean ± SEM; Two-tailed t test was used for the statistical analysis. **P<0.05.