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Transcriptional regulation of miR-483-3p mediated by IL-6/STAT3 axis promoted epithelial-mesenchymal transition and tumor stemness in glioma

STAT3 was activated in U251 and U87 cells. (A, B) qRT-PCR analysis showed upregulation of STAT3 in cancer tissues and different cancer cell lines. Data are mean ± SEM; Two-tailed t test was used for the statistical analysis. n= 39 glioma patients or 5 independent cell cultures. (C) Western bolt analysis showed protein levels of STAT3 in different cancer cell lines. Data are mean ± SEM; Two-tailed t test was used for the statistical analysis. n=5 independent cell cultures. **P

Figure 5. STAT3 was activated in U251 and U87 cells. (A, B) qRT-PCR analysis showed upregulation of STAT3 in cancer tissues and different cancer cell lines. Data are mean ± SEM; Two-tailed t test was used for the statistical analysis. n= 39 glioma patients or 5 independent cell cultures. (C) Western bolt analysis showed protein levels of STAT3 in different cancer cell lines. Data are mean ± SEM; Two-tailed t test was used for the statistical analysis. n=5 independent cell cultures. **P<0.05.