Research Paper Volume 12, Issue 24 pp 24967—24982

HBXIP promotes gastric cancer via METTL3-mediated MYC mRNA m6A modification

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Figure 7. The growth of GC xenografts is inhibited by silencing HBXIP in vivo. (A) Representative images of transplanted tumors in nude mice injected with MKN-45 cells. (B) The volume of transplanted tumors monitored every 3 days in nude mice injected with MKN-45 cells. (C) Weight of transplanted tumors in nude mice injected with MKN-45 cells. * p < 0.05 vs. the sh-NC group (nude mice injected with sh-NC-treated MKN-45 cells). Measurement data were expressed as mean ± standard deviation. Data in panel (C) were compared by unpaired t-test and in panel B by repeated measures ANOVA with Bonferroni post hoc test. n = 6.