Research Paper Volume 12, Issue 24 pp 24967—24982

HBXIP promotes gastric cancer via METTL3-mediated MYC mRNA m6A modification

Figure 7. The growth of GC xenografts is inhibited by silencing HBXIP in vivo. (A) Representative images of transplanted tumors in nude mice injected with MKN-45 cells. (B) The volume of transplanted tumors monitored every 3 days in nude mice injected with MKN-45 cells. (C) Weight of transplanted tumors in nude mice injected with MKN-45 cells. * p < 0.05 vs. the sh-NC group (nude mice injected with sh-NC-treated MKN-45 cells). Measurement data were expressed as mean ± standard deviation. Data in panel (C) were compared by unpaired t-test and in panel B by repeated measures ANOVA with Bonferroni post hoc test. n = 6.