Research Paper Volume 12, Issue 17 pp 17541—17567

BRD4/8/9 are prognostic biomarkers and associated with immune infiltrates in hepatocellular carcinoma

Figure 4. The association between mRNA expression of 7 distinct BRD-containing protein genes and HCC tumor grades from TCGA database (UALCAN). mRNA expressions of 7 BRD-containing protein genes were remarkably correlated with tumor grades. Along with the severity of histological grade in HCC, the mRNA expressions of 7 BRD-containing protein genes elevated. The highest mRNA expressions of BRD4/8/9 were found in tumor grade 4 (D, F, G), while the highest mRNA expressions of BRD1/2/3/7 were found in tumor grade 3 (AC, E). *P < 0.05, **P < 0.01, ***P < 0.001.