Research Paper Volume 12, Issue 17 pp 17568—17581

HSPB8 overexpression prevents disruption of blood-brain barrier after intracerebral hemorrhage in rats through Akt/GSK3β/β-catenin signaling pathway

Figure 1. HSPB8 expression was increased upon ICH. (A) Representative western blot bands for HSPB8 expression in sham and ICH rats 3, 6, 12, 24, and 72 h following ICH. (B) Densitometric quantification of HSPB8 for the western blot (n=6, mean±SEM). (C) Representative images of immunofluorescence staining for HSPB8 and CD31 in control and ICH (D) Representative images of immunofluorescence staining for HSPB8 and GFAP in control and ICH. Scale bars = 50 μm (n =4, mean±SEM). *P <0.05 versus sham group; **P<0.01 versus sham group. n=number of animals per group.