Research Paper Volume 12, Issue 19 pp 19316—19324

SYNE1 mutation may enhance the response to immune checkpoint blockade therapy in clear cell renal cell carcinoma patients


Tumor-infiltrating immune cells associated with SYNE1 mutation in ccRCC. (A) Bar chart of infiltration of 22 immune cells. (B) Boxplot showing differentially infiltrating immune cells based on SYNE1 mutation. Red color represents the mt group and blue represents the wt group. (C) Correlation matrix of immune cell fractions. The blue color represents positive correlation, and red represents negative correlation.