Research Paper Volume 12, Issue 19 pp 19316—19324

SYNE1 mutation may enhance the response to immune checkpoint blockade therapy in clear cell renal cell carcinoma patients

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Predicting of ICB response based on SYNE1 mutation and biomarker evaluation. (A) Violin plot showing the differential TIDE between the mt and wt groups. (B) Evaluation of SYNE1 as a biomarker compared with existing biomarkers. (C) Multivariate analysis of SYNE1 and existing biomarkers using the COX proportional hazards model.