Research Paper Volume 13, Issue 2 pp 1859—1871

Development of prognostic signature based on immune-related genes in muscle-invasive bladder cancer: bioinformatics analysis of TCGA database

Differentially expressed transcription factors and regulation network. Heatmap (A) and volcano plot (B) showing different expressed transcription factors, green dots represent down-regulated and red dots represent up-regulated. And regulation network (C) presenting association of TFs and IRGs, red circles represent high risk genes and blue triangle represent TFs, while the red line represent up-regulated effects.

Figure 3. Differentially expressed transcription factors and regulation network. Heatmap (A) and volcano plot (B) showing different expressed transcription factors, green dots represent down-regulated and red dots represent up-regulated. And regulation network (C) presenting association of TFs and IRGs, red circles represent high risk genes and blue triangle represent TFs, while the red line represent up-regulated effects.