Research Paper Volume 13, Issue 11 pp 15638—15658

Transfer of exosomal microRNA-203-3p from dendritic cells to bone marrow-derived macrophages reduces development of atherosclerosis by downregulating Ctss in mice

The mechanism diagram shows that transfer of exosomal miR-203-3p from dendritic cells to BMDMs reduces BMDM-derived foam cells and the levels of TC, FC and CE by impairing Ctss expression, thus suppressing the development of atherosclerosis.

Figure 9. The mechanism diagram shows that transfer of exosomal miR-203-3p from dendritic cells to BMDMs reduces BMDM-derived foam cells and the levels of TC, FC and CE by impairing Ctss expression, thus suppressing the development of atherosclerosis.