Research Paper Volume 12, Issue 18 pp 18622—18634

Asymmetrical nigral iron accumulation in Parkinson’s disease with motor asymmetry: an explorative, longitudinal and test-retest study

Figure 2. Longitudinal alterations of regional tissue susceptibility showing statistical significance. (A) PD patients with significant motor asymmetry were defined by conservative criteria according to the distribution of differences scores between bilateral motor scores (mean ± 1 SD), and 25 PD patients were included; (B) PD patients with significant motor asymmetry were defined by slacked criteria (mean ± 0.5 SD) and 30 PD patients were included. The post hoc t-test for each pair of regional tissue susceptibility at baseline and follow-up was conducted, t value and p value are shown. SN = Substantia nigra; GP = Globus pallidus; RN = Red nucleus.