Research Paper Volume 12, Issue 18 pp 17815—17844

Alzheimer’s disease as a systems network disorder: chronic stress/dyshomeostasis, innate immunity, and genetics

Figure 2. The network of genetic polymorphisms associated with Alzheimer’s disease. Most of the genetic polymorphisms associated with Alzheimer’s disease can be broadly assigned to a small number of overlapping functional groups and interconnected via such terms as tissue damage and repair, innate immune activation, inflammation, wound clearance, and detoxification, without specifying whether these processes occur in the CNS or on the periphery.