Research Paper Volume 12, Issue 16 pp 15995—16020

Neuroprotective effects of p62(SQSTM1)-engineered lactic acid bacteria in Alzheimer’s disease: a pre-clinical study

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Figure 7. Treatment effects on proteins, lipids and DNA oxidation. Determination of carbonyls and 3-NT (panel A), 4-HNE (panel B), 8-oxodG and OGG1 (panel C) in brain homogenates of 3xTg-AD mice (T0, C, LAB and p62-LAB groups). GAPDH was used as a control to check equal protein loading (*p<0.05, **p<0.01 and ***p<0.001 vs T0, ##p<0.01 and ###p<0.001 vs C, §p<0,05, §§p<0.01 and §§§p<0.001 vs LAB).