Research Paper Volume 12, Issue 22 pp 22776—22793

Immune-related biomarker risk score predicts prognosis in prostate cancer

Figure 10. PLK1 expression correlated positively with M2 macrophage infiltration. (A) Fluorescence imaging of human prostate cancer and adjacent noncancerous tissues with FITC-labeled CD163 and Cy3-labeled PLK1. Most green fluorescent signals were observed on the cytomembrane, while red fluorescent signals were primarily located in the cytoplasm in prostate tissue. (B) Numbers of green fluorescent cells and red fluorescence integral optical density were positively correlated in prostate cancer samples (r2=0.51, p<0.01). (C) PLK1 staining was more intense in prostate cancer tissues than in non-cancerous prostate tissues.