Research Paper Volume 12, Issue 18 pp 17863—17894

Epigenetic mutation load is weakly correlated with epigenetic age acceleration

Figure 1. Heatmap of pairwise correlations of chronological age and epigenetic age accelerations. The heat map color-codes the pairwise Pearson correlations of chronological age and epigenetic age accelerations in the Framingham Heart Study (N=2326). Age represents the chronological age. AgeAccelHorvath, IEAA, AgeAccelHannum, and AgeAccelGrim represent measures of epigenetic age acceleration derived from the Horvath pan tissue clock, the intrinsic clock, the Hannum clock, and the GrimAge clock, respectively. The shades of color (blue, white, and red) visualize correlation values from -1 to 1. Each square reports a Pearson correlation coefficient.