Research Paper Volume 12, Issue 22 pp 22859—22868

Identification of novel FUS and TARDBP gene mutations in Chinese amyotrophic lateral sclerosis patients with HRM analysis

Figure 3. A novel 3′UTR mutation, c. *731A>G in the TARDBP gene identified in a Chinese ALS patient. (A) The novel 3′UTR mutation was identified by HRM analysis and direct sequencing. (B) The evolutionary conservation of the TARDBP 3′UTR mutation c. *731A>G.