Research Paper Volume 12, Issue 24 pp 25020—25034

TRIB3 facilitates glioblastoma progression via restraining autophagy

Figure 4. TRIB3 promotes glioma growth and metastasis in vivo. (A) Quantitative analysis of the tumor volume at the indicated times. (B) Quantitative analysis of the tumor weight. (C) HE staining and Ki-67 and CD34 immunohistological staining of tumors derived from scramble and sh-TRIB3 cells. (D) In vivo bioluminescent imaging of nude mice at days 7, 14, and 28 post-GBM cell implantation. Quantification of luminescence signal intensity on days 7, 14, and 28 after implanting the GBM cells. *p<0.05, **p< 0.01.