Research Paper Volume 12, Issue 18 pp 18716—18740
Identification of robust genetic signatures associated with lipopolysaccharide-induced acute lung injury onset and astaxanthin therapeutic effects by integrative analysis of RNA sequencing data and GEO datasets
Figure 3. Visualization of DEGs identified by RNA sequencing and the overlap of the results with the meta-analysis of the five microarrays. (A) Volcano plot representation of the1187 DEGs associated with LPS-induced ALI onset identify by RNA sequencing (control group vs. LPS group). (B) Volcano plot representation of the 21 DEGs associated with the AST therapeutic effect of AST identified by RNA sequencing (LPS group vs. AST group). (C) Heat map of the 181 overlapping upregulated genes identified by both meta-analysis of published microarrays and our RNA sequencing experiments (control group vs. LPS group).