Priority Research Paper Volume 12, Issue 20 pp 19852—19866

Metformin alters skeletal muscle transcriptome adaptations to resistance training in older adults

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Figure 2.

Pathway overrepresentation analyses on differentially expressed genes (DEG). (A) Pathways overrepresented in plaPRT-induced DEG with the length of the bar representing the number of DEG (upregulated genes to the right and downregulated genes to the left); (B) Pathways overrepresented in metPRT-induced DEG; (C) Common pathways overrepresented between the plaPRT (orange) and metPRT (green) groups; (D) Pathways overrepresented in the 517 DEG within the metPRT group that do not overlap with the DEG for the plaPRT group.