Priority Research Paper Volume 12, Issue 20 pp 19852—19866

Metformin alters skeletal muscle transcriptome adaptations to resistance training in older adults

Figure 2. Pathway overrepresentation analyses on differentially expressed genes (DEG). (A) Pathways overrepresented in plaPRT-induced DEG with the length of the bar representing the number of DEG (upregulated genes to the right and downregulated genes to the left); (B) Pathways overrepresented in metPRT-induced DEG; (C) Common pathways overrepresented between the plaPRT (orange) and metPRT (green) groups; (D) Pathways overrepresented in the 517 DEG within the metPRT group that do not overlap with the DEG for the plaPRT group.