Research Paper Volume 12, Issue 24 pp 25614—25642

Identification of prognostic chromatin-remodeling genes in clear cell renal cell carcinoma

Figure 1. Consensus clustering algorithm identified two clusters with prognostic value. (A) 496 TCGA-KIRC patients were group into a consensus matrix with Cluster A (n=206) and Cluster B (n=290) based on 86 chromatin-remodeling factors and consensus clustering algorithm. (B) Consensus matrix among cumulative distribution function (CDF) curves from 2 to 10 clusters. (C) Relative changes in delta area under the CDF curve for each k category from 2 to 10. (D) Comparison of overall prognostic differences between Cluster A and Cluster B upon all stage patients. (E) Comparison of progression-free prognostic differences between Cluster A and Cluster B upon all stage patients.