Research Paper Volume 13, Issue 3 pp 3342—3352

The DNA methylation-regulated MCTP1 activates the drug-resistance of esophageal cancer cells

Differential methylation of the MCTP1 gene in seven esophageal cancer cell lines. (A) BSP primers and CpG dinucleotides of MCTP1 are shown. (B) Relative methylation levels (fold) of MCTP1 in seven esophageal cancer cell lines. (C) Methylation percentage at seven CpG sites in seven esophageal cancer cell lines. (D)The percentage of CpG methylation is summarized in Kyse450 and Kyse510 cells. (E) The original sequencing results of the bisulfite-converted DNA are shown in Kyse450 and Kyse510 cells.

Figure 2. Differential methylation of the MCTP1 gene in seven esophageal cancer cell lines. (A) BSP primers and CpG dinucleotides of MCTP1 are shown. (B) Relative methylation levels (fold) of MCTP1 in seven esophageal cancer cell lines. (C) Methylation percentage at seven CpG sites in seven esophageal cancer cell lines. (D)The percentage of CpG methylation is summarized in Kyse450 and Kyse510 cells. (E) The original sequencing results of the bisulfite-converted DNA are shown in Kyse450 and Kyse510 cells.