Research Paper Volume 13, Issue 3 pp 3342—3352

The DNA methylation-regulated MCTP1 activates the drug-resistance of esophageal cancer cells

MCTP1 expression level affecting cell proliferation and apoptosis. (A) The cell proliferation assays showed the lower proliferation capacity of Kyse450 cells when transfected with three different regions’ si-MCTP1 versus the negative control (NC). (B) The higher proliferation capacity of Kyse510 cells infected with MCTP1 overexpression lentivirus vector versus the negative control (NC). (C, D) FACS analysis of the effects of the three different regions’ si-MCTP1 versus the negative control (NC) on apoptosis in Kyse450 cells.

Figure 5. MCTP1 expression level affecting cell proliferation and apoptosis. (A) The cell proliferation assays showed the lower proliferation capacity of Kyse450 cells when transfected with three different regions’ si-MCTP1 versus the negative control (NC). (B) The higher proliferation capacity of Kyse510 cells infected with MCTP1 overexpression lentivirus vector versus the negative control (NC). (C, D) FACS analysis of the effects of the three different regions’ si-MCTP1 versus the negative control (NC) on apoptosis in Kyse450 cells.