A SNP involved in alternative splicing of <i>ABCB1</i> is associated with clopidogrel resistance in coronary heart disease in Chinese population

Shasha Zhang; Jing Wang; Anan Zhang; Xiaowei Zhang; Tao You; Dingxiong Xie; Wenke Yang; Yuhong Chen; Xuetian Zhang; Cuixia Di; Xiaodong Xie

doi:doi:10.18632/aging.104177

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Research Paper Volume 12, Issue 24 pp 25684—25699

A SNP involved in alternative splicing of ABCB1 is associated with clopidogrel resistance in coronary heart disease in Chinese population

Figure 3. Linkage disequilibrium plot and r² values for five polymorphisms of the ABCB1 gene. (A) D′ plot of five polymorphic linkage disequilibrium. (B) r² plot of five polymorphic linkage disequilibrium. Linkage disequilibrium was detected in the rs3789243 and rs1858923 polymorphisms ((r² = 0.310, D′ = 0.815), rs1858923 and rs4148727 polymorphisms (r² = 0.070, D′ = 0.872).