Research Paper Volume 13, Issue 1 pp 351—363

ADRB1 was identified as a potential biomarker for breast cancer by the co-analysis of tumor mutational burden and immune infiltration

The landscape of mutation genes in BRCA samples. (A) Classification of mutation types according to different categories, in which missense mutation accounts for the most fraction; SNP appears in all mutations; and C>T is the most common SNV; tumor mutational burden in specific samples; the top 10 mutated genes in BC. (B) Mutation information of each gene in each sample is shown in the waterfall plot, in which various colors with annotations at the bottom represent the different mutation types. The bar plot above the legend shows the tumor mutational burden; (C) The coincident and exclusive associations across mutated genes. SNP, single nucleotide polymorphism; SNV, single nucleotide variants; BRCA, breast cancer.

Figure 1. The landscape of mutation genes in BRCA samples. (A) Classification of mutation types according to different categories, in which missense mutation accounts for the most fraction; SNP appears in all mutations; and C>T is the most common SNV; tumor mutational burden in specific samples; the top 10 mutated genes in BC. (B) Mutation information of each gene in each sample is shown in the waterfall plot, in which various colors with annotations at the bottom represent the different mutation types. The bar plot above the legend shows the tumor mutational burden; (C) The coincident and exclusive associations across mutated genes. SNP, single nucleotide polymorphism; SNV, single nucleotide variants; BRCA, breast cancer.