Research Paper Volume 13, Issue 1 pp 450—459

Comparative efficacy, safety, and acceptability of single-agent poly (ADP-ribose) polymerase (PARP) inhibitors in BRCA-mutated HER2-negative metastatic or advanced breast cancer: a network meta-analysis

Forest plots comparing PFS for talazoparib, olaparib, and TPC (subgroup analysis). (A) Hormone receptor–positive patients; (B) patients with TNBC; (C) patients with prior platinum; (D) patients with no prior platinum; (E) patients with BRCA1 mutation; (F) patients with BRCA2 mutation; (G) patients who received no prior chemotherapy.

Figure 4. Forest plots comparing PFS for talazoparib, olaparib, and TPC (subgroup analysis). (A) Hormone receptor–positive patients; (B) patients with TNBC; (C) patients with prior platinum; (D) patients with no prior platinum; (E) patients with BRCA1 mutation; (F) patients with BRCA2 mutation; (G) patients who received no prior chemotherapy.