Research Paper Volume 12, Issue 24 pp 25939—25955

Sexual dimorphism in aging hematopoiesis: an earlier decline of hematopoietic stem and progenitor cells in male than female mice

Figure 2. Comparisons of relative hematopoietic gene expression in BM-derived LSK cells among young, middle-aged and old mice of both male and female mice. (A) Comparison between middle-aged male and young male mice. (B) Comparison between old male and young male mice. (C) Comparison between old male and middle-aged male mice. (D) Comparison between middle-aged female and young female mice. (E) Comparison between old female and young female mice. (F) Comparison between old female and middle-aged female mice. Yellow dots indicate genes with potentially higher level of expression in mice of y-axis than that in mice of x-axis; black dots indicate genes with comparable level of expression; blue dots indicate genes with potentially lower level of expression in mice of y-axis than that in mice of x-axis.