Figure 5. EPHA5 mutation is correlated with increased TMB and occurred concurrently with DNA repair pathways in Chinses LUAD patients. (A) Mutational landscape of the Chinese LUAD cohort. (B) EPHA5-Mut tumors had a markedly higher TMB than EPHA5-WT tumors. (C) EPHA5 mutations occurred concurrently with HR and MMR pathways. Markedly higher proportion of (D) HR and (E) MMR pathway mutations were observed in EPHA5-Mut group.