Research Paper Volume 13, Issue 1 pp 181—193

The adhesion molecule ICAM-1 in diffuse large B-cell lymphoma post-rituximab era: relationship with prognostic importance and rituximab resistance

Progression-free survival (PFS) and overall survival (OS) of DLBCL patients in our study. Kaplan-Meier curves showing the association between ICAM-1 expression and PFS (A), OS (B) of DLBCL patients treated with CHOP regimen. R-CHOP could significantly improve PFS (C) and OS (D) in ICAM-1 negative expression patient compared to CHOP patients. In ICAM-1 positive patient, no statistical difference of PFS (E) and OS (F) between R-CHOP and CHOP group. All the P values are shown in the graph, by log-rank test.

Figure 2. Progression-free survival (PFS) and overall survival (OS) of DLBCL patients in our study. Kaplan-Meier curves showing the association between ICAM-1 expression and PFS (A), OS (B) of DLBCL patients treated with CHOP regimen. R-CHOP could significantly improve PFS (C) and OS (D) in ICAM-1 negative expression patient compared to CHOP patients. In ICAM-1 positive patient, no statistical difference of PFS (E) and OS (F) between R-CHOP and CHOP group. All the P values are shown in the graph, by log-rank test.