Research Paper Volume 13, Issue 1 pp 750—768

KRAS mutations are negatively correlated with immunity in colon cancer

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Figure 2.

Survival analysis of KRAS mutations in colon cancer. (AD) The survival rate of patients with different base-pairs in rs112445441, rs121913527, rs121913529, and rs121913530. (E, F) Comparison of the survival rates between KRAS-mutated and wild-type patients from the ICGC and TCGA databases. The difference in survival rate was statistically significant in ICGC (P=0.04), but not in TCGA (P=0.8469). In TCGA analysis, there were 171 and 225 patients with and without KRAS mutations, respectively. In ICGC analysis, there were 112 and 196 patients with and without KRAS mutations, respectively.