Research Paper Volume 13, Issue 1 pp 769—781

The microRNA miR-29c-5p inhibits cell proliferation and migration by targeting TMEM98 in head and neck carcinoma

Analysis of a mouse tumor xenograft model of HNSCC. (A) Significantly lower tumor volumes were observed in mice xenografted with HNSCC cells transfected with miR-29c-5p mimic compared with control. (B, C) Tumor weights were significantly lower in mice xenografted with cells transfected with the miR-29c-5p mimic compared with control. (D) Ki67 and TMEM98 expression was detected in tumor tissues formed by xenografted HNSCC cells transfected with the miR-29c-5p mimics. *p E) Bar graph indicates quantitative analysis of the percentage of Ki-67 positive cells in either miR-29c-5p mimic group or control group.

Figure 7. Analysis of a mouse tumor xenograft model of HNSCC. (A) Significantly lower tumor volumes were observed in mice xenografted with HNSCC cells transfected with miR-29c-5p mimic compared with control. (B, C) Tumor weights were significantly lower in mice xenografted with cells transfected with the miR-29c-5p mimic compared with control. (D) Ki67 and TMEM98 expression was detected in tumor tissues formed by xenografted HNSCC cells transfected with the miR-29c-5p mimics. *p < 0.05, **p < 0.01. (E) Bar graph indicates quantitative analysis of the percentage of Ki-67 positive cells in either miR-29c-5p mimic group or control group.