Research Paper Volume 13, Issue 1 pp 831—845

Atorvastatin improves motor function, anxiety and depression by NOX2-mediated autophagy and oxidative stress in MPTP-lesioned mice

Atorvastatin rescues the expression of antioxidant stress Nrf2, HO-1 and NQO-1 (A–D) by inhibiting NOX2 in MPTP mice. The results are expressed as *p **p ***p #p ##p

Figure 9. Atorvastatin rescues the expression of antioxidant stress Nrf2, HO-1 and NQO-1 (AD) by inhibiting NOX2 in MPTP mice. The results are expressed as *p < 0.05 or **p < 0.01 or ***p < 0.001; NS indicates no significance compared to MPTP/atorvastatin/NOX2-shRNA (-/-/-). The results are expressed as #p < 0.05 or ##p < 0.05 compared to MPTP/atorvastatin/NOX2-shRNA (+/-/-).