Research Paper Volume 13, Issue 1 pp 894—909

The emerging role of the MiR-1272-ADAM9-CDCP1 signaling pathway in the progression of glioma

MiR-1272 is downregulated in glioma tissues and is negatively correlated with ADAM9. (A) ADAM9 showed increased expression in glioma tissues compared with their adjacent tissues, as assessed by western blotting. (B) Relative expression of miR-1272 in glioma tissues, as assessed by qRT-PCR. (C) Opposite expression patterns of miR-1272 and ADAM9 in clinical glioma tissues. (D) Upregulation of ADAM9 in clinical glioma tissues derived from the TCGA database. (E) ADAM9 expression in clinical glioma tissues was associated with malignant grade. Error bars represent mean ± SEM. * p

Figure 5. MiR-1272 is downregulated in glioma tissues and is negatively correlated with ADAM9. (A) ADAM9 showed increased expression in glioma tissues compared with their adjacent tissues, as assessed by western blotting. (B) Relative expression of miR-1272 in glioma tissues, as assessed by qRT-PCR. (C) Opposite expression patterns of miR-1272 and ADAM9 in clinical glioma tissues. (D) Upregulation of ADAM9 in clinical glioma tissues derived from the TCGA database. (E) ADAM9 expression in clinical glioma tissues was associated with malignant grade. Error bars represent mean ± SEM. * p < 0.05, ** p < 0.01, *** p < 0.001.