Research Paper Volume 13, Issue 2 pp 2073—2088

Decreased expression of JAK1 associated with immune infiltration and poor prognosis in lung adenocarcinoma

Enrichment plots from GSEA. GSEA results indicated that the JAK-STAT signaling pathway (A), the non-small cell lung cancer (B), the MARK signaling pathway (C), the ERBB signaling pathway (D), the focal adhesion, (E), the B cell receptor signaling pathway (F), the T cell receptor signaling pathway (G), the natural killer mediated cytotoxicity (H), and leukocyte transendothelial migration (I) were differentially enriched in LUAD samples with high JAK1 expression. NES, normalized enrichment score; NOM p-val, normalized P-value; FDR q-val, false discovery rate q-value; GSEA, Gene Set Enrichment Analysis.

Figure 5. Enrichment plots from GSEA. GSEA results indicated that the JAK-STAT signaling pathway (A), the non-small cell lung cancer (B), the MARK signaling pathway (C), the ERBB signaling pathway (D), the focal adhesion, (E), the B cell receptor signaling pathway (F), the T cell receptor signaling pathway (G), the natural killer mediated cytotoxicity (H), and leukocyte transendothelial migration (I) were differentially enriched in LUAD samples with high JAK1 expression. NES, normalized enrichment score; NOM p-val, normalized P-value; FDR q-val, false discovery rate q-value; GSEA, Gene Set Enrichment Analysis.