Research Paper Volume 13, Issue 1 pp 1132—1152

Ginsenoside RG1 enhances the paracrine effects of bone marrow-derived mesenchymal stem cells on radiation induced intestinal injury

Conditioned medium from BM-MSCs pre-activated by RG1 (RG1-MSC-CM) releases higher concentrations of VEGF and IL-6, and protects against RIII via improvement of intestinal regeneration, inflammation, angiogenesis and stem cell regeneration in a heme oxygenase-1 dependent mechanism.

Figure 11. Conditioned medium from BM-MSCs pre-activated by RG1 (RG1-MSC-CM) releases higher concentrations of VEGF and IL-6, and protects against RIII via improvement of intestinal regeneration, inflammation, angiogenesis and stem cell regeneration in a heme oxygenase-1 dependent mechanism.