Research Paper Volume 12, Issue 24 pp 26029—26046

DUSP5 suppresses interleukin-1β-induced chondrocyte inflammation and ameliorates osteoarthritis in rats

Figure 2. The expression of DUSP5 in SD rat chondrocytes. (A, B) The protein expression and quantitation of DUSP5 in SD rat chondrocytes incubated with IL-1β at 0, 5, 10, and 20 ng/mL for 24 h. (C, D) The protein expression and quantitation of DUSP5 in SD rat chondrocytes incubated with IL-1β at 10 ng/mL for 0, 6, 12, and 24 h. (E, F) The protein expression and quantitation of DUSP5 in SD rat chondrocytes incubated with IL-1β at 10 ng/mL for 0, 6, 12, 24, 48, 72, and 96 h. The medium and IL- 1β were added at time Zero. Then every 24 hours changed the medium and re-added IL- 1β. GAPDH was used as the control. All data are expressed as mean±S.D. (n = 3). *p<0.05, **p<0.01.