Research Paper Volume 13, Issue 1 pp 1186—1211

MicroRNA-139-5p upregulation is associated with diabetic endothelial cell dysfunction by targeting c-jun

MiR-139-5p-mediated c-jun expression regulates the function of ECFCs. The migration (A) and angiogenesis (B) of normal ECFCs were co-transfected with miR-139-5p mimics and c-jun plasmids and diabetic ECFCs were co-transfected with miR-139-5p inhibitors and c-jun siRNA. The photos were captured by a 40X fluorescence microscope. (N=3) *P

Figure 6. MiR-139-5p-mediated c-jun expression regulates the function of ECFCs. The migration (A) and angiogenesis (B) of normal ECFCs were co-transfected with miR-139-5p mimics and c-jun plasmids and diabetic ECFCs were co-transfected with miR-139-5p inhibitors and c-jun siRNA. The photos were captured by a 40X fluorescence microscope. (N=3) *P < .05 versus control. Data shown in the graphs represent mean ± standard deviation.