Figure 6. PTP1B inhibitor treatment weakened the protein interaction between PTP1B and phospho-PERK in primary microglia under oxygen glucose deprivation/reoxygenation (OGD/R) conditions. (A) Proximity ligation assay (PLA) probe was used to examine the proximity between PTP1B and phospho-PERK. Scale bar = 20 μm. (B) The average number of blobs per nuclei per image was quantified as the mean ± SEM (n = 6 per group). *p < 0.05 compared with vehicle group; ***p < 0.001 compared with sham group; sc = PTP1B inhibitor sc-222227; p-PERK = phospho-PERK; OGD/R = oxygen glucose deprivation/reoxygenation.