Research Paper Advance Articles pp 24117—24133

Dilated cardiomyopathy impairs mitochondrial biogenesis and promotes inflammation in an age- and sex-dependent manner

Figure 3. DCM-related alterations in expression of mitochondrial genes in older patients. Real-time PCR analysis for the mitochondrial-encoded genes cox1 (A, B) and mt-nda (C, D) as well as the nuclear-encoded genes ndusf1 (E, F), performed with human cardiac tissue lysates from old control (non-diseased) or DCM men (♂) and women (♀). Data are shown as the mean ± SEM (n= 5).